ICSC 1742 - HYDROXYPROPYL ACRYLATE, ISOMERS

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HYDROXYPROPYL ACRYLATE, ISOMERS	ICSC: 1742 (March 2009)
Propylene glycol monoacrylate Acrylic acid, monoester with propane-1,2-diol 2-Propenoic acid, monoester with propane-1,2-diol

CAS #: 25584-83-2

UN #: 2810

EC Number: 247-118-0

	ACUTE HAZARDS	PREVENTION	FIRE FIGHTING
FIRE & EXPLOSION	Combustible. Gives off irritating or toxic fumes (or gases) in a fire. Above 97°C explosive vapour/air mixtures may be formed.	NO open flames. Above 97°C use a closed system and ventilation.	Use water spray, dry powder, alcohol-resistant foam, carbon dioxide. In case of fire: keep drums, etc., cool by spraying with water.

AVOID ALL CONTACT! PREVENT GENERATION OF MISTS!
	SYMPTOMS	PREVENTION	FIRST AID
Inhalation	Cough. Sore throat. Burning sensation.	Use ventilation, local exhaust or breathing protection.	Fresh air, rest. Refer for medical attention.
Skin	MAY BE ABSORBED! Redness. Pain.	Protective gloves. Protective clothing.	Remove contaminated clothes. Rinse skin with plenty of water or shower. Refer for medical attention .
Eyes	Redness. Pain.	Wear face shield or eye protection in combination with breathing protection.	Rinse with plenty of water (remove contact lenses if easily possible). Refer for medical attention.
Ingestion	Abdominal pain. Burning sensation in the throat and chest. Vomiting.	Do not eat, drink, or smoke during work.	Rinse mouth. Do NOT induce vomiting. Refer for medical attention .

SPILLAGE DISPOSAL	CLASSIFICATION & LABELLING
Personal protection: chemical protection suit and filter respirator for organic gases and vapours adapted to the airborne concentration of the substance. Do NOT let this chemical enter the environment. Collect leaking liquid in covered containers. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations.	According to UN GHS Criteria DANGER Harmful if swallowed Toxic in contact with skin Causes skin irritation Causes serious eye irritation May cause an allergic skin reaction May cause respiratory irritation May be harmful if swallowed and enters airways Toxic to aquatic life Transportation UN Classification UN Hazard Class: 6.1; UN Pack Group: II
STORAGE
Separated from food and feedstuffs, strong bases and strong acids. Store only if stabilized. See Notes. Cool. Keep in the dark. Store in an area without drain or sewer access. Provision to contain effluent from fire extinguishing.
PACKAGING
Do not transport with food and feedstuffs.

HYDROXYPROPYL ACRYLATE, ISOMERS

ICSC: 1742

PHYSICAL & CHEMICAL INFORMATION
Physical State; Appearance COLOURLESS LIQUID. Physical dangers No data. Chemical dangers The substance may polymerize due to heating and under the influence of light, and peroxides. Decomposes on heating. This produces toxic and corrosive fumes including acrolein. Reacts violently with strong acids, strong bases, strong oxidants and peroxides. This generates fire hazard.	Formula: C₆H₁₀O₃ Molecular mass: 130.1 Boiling point: 205.7°C Melting point: -23.4°C Density: 1.05 g/cm³ Solubility in water, g/100ml at 25°C: 30.7 (good) Vapour pressure, Pa at 25°C: 4 Relative vapour density (air = 1): 4.5 Relative density of the vapour/air-mixture at 20°C (air = 1): 1.00 Flash point: 97°C c.c. Explosive limits, vol% in air: 1.8-? Octanol/water partition coefficient as log Pow: 0.35 Viscosity: 8.2 mm²/s at 20°C

PHYSICAL & CHEMICAL INFORMATION

Physical State; Appearance
COLOURLESS LIQUID.

Physical dangers
No data.

Chemical dangers
The substance may polymerize due to heating and under the influence of light, and peroxides. Decomposes on heating. This produces toxic and corrosive fumes including acrolein. Reacts violently with strong acids, strong bases, strong oxidants and peroxides. This generates fire hazard.

Formula: C₆H₁₀O₃
Molecular mass: 130.1
Boiling point: 205.7°C
Melting point: -23.4°C
Density: 1.05 g/cm³
Solubility in water, g/100ml at 25°C: 30.7 (good)
Vapour pressure, Pa at 25°C: 4
Relative vapour density (air = 1): 4.5
Relative density of the vapour/air-mixture at 20°C (air = 1): 1.00
Flash point: 97°C c.c.
Explosive limits, vol% in air: 1.8-?
Octanol/water partition coefficient as log Pow: 0.35
Viscosity: 8.2 mm²/s at 20°C

EXPOSURE & HEALTH EFFECTS
Routes of exposure The substance can be absorbed into the body through the skin and by ingestion. Effects of short-term exposure The substance is severely irritating to the skin and eyes. The substance is irritating to the respiratory tract. If swallowed the substance may cause vomiting and could result in aspiration pneumonitis.	Inhalation risk A harmful contamination of the air will be reached rather slowly on evaporation of this substance at 20°C. Effects of long-term or repeated exposure Repeated or prolonged contact with skin may cause dermatitis. Repeated or prolonged contact may cause skin sensitization. See Notes.

EXPOSURE & HEALTH EFFECTS

Routes of exposure
The substance can be absorbed into the body through the skin and by ingestion.

Effects of short-term exposure
The substance is severely irritating to the skin and eyes. The substance is irritating to the respiratory tract. If swallowed the substance may cause vomiting and could result in aspiration pneumonitis.

Inhalation risk
A harmful contamination of the air will be reached rather slowly on evaporation of this substance at 20°C.

Effects of long-term or repeated exposure
Repeated or prolonged contact with skin may cause dermatitis. Repeated or prolonged contact may cause skin sensitization. See Notes.

OCCUPATIONAL EXPOSURE LIMITS
MAK sensitization of skin (SH)

ENVIRONMENT
The substance is toxic to aquatic organisms. It is strongly advised not to let the chemical enter into the environment.

NOTES
Do NOT take working clothes home. Skin cross-sensitization with other acrylates is possible. A typical commercial sample of hydroxypropyl acrylate contains approximately 75-80% 2-hydroxypropyl acrylate and 20-25% 1-methyl-2- hydroxyethyl acrylate. The purity of the saleable product is at least 97% combined isomers. See ICSC 0899. An added stabilizer or inhibitor can influence the toxicological properties of this substance, consult an expert. The effectiveness of phenolic inhibitors is dependent on the presence of oxygen. Store under air rather than inert atmosphere.

NOTES

Do NOT take working clothes home.
Skin cross-sensitization with other acrylates is possible.
A typical commercial sample of hydroxypropyl acrylate contains approximately 75-80% 2-hydroxypropyl acrylate and 20-25% 1-methyl-2- hydroxyethyl acrylate. The purity of the saleable product is at least 97% combined isomers.
See ICSC 0899.
An added stabilizer or inhibitor can influence the toxicological properties of this substance, consult an expert.
The effectiveness of phenolic inhibitors is dependent on the presence of oxygen. Store under air rather than inert atmosphere.

ADDITIONAL INFORMATION

EC Classification
Symbol: T; R: 23/24/25-34-43; S: (1/2)-26-36/37/39-45; Note: C, D

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