ICSC 1441 - o-PHENYLENEDIAMINE

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o-PHENYLENEDIAMINE	ICSC: 1441 (September 2002)
2-Aminoaniline 1,2-Phenylenediamine o-Diaminobenzene 1,2-Benzenediamine

CAS #: 95-54-5

UN #: 1673

EC Number: 202-430-6

	ACUTE HAZARDS	PREVENTION	FIRE FIGHTING
FIRE & EXPLOSION	Combustible. Gives off irritating or toxic fumes (or gases) in a fire. Finely dispersed particles form explosive mixtures in air.	NO open flames. Closed system, dust explosion-proof electrical equipment and lighting. Prevent deposition of dust.	Use water spray, powder.

STRICT HYGIENE!
	SYMPTOMS	PREVENTION	FIRST AID
Inhalation	Blue lips, fingernails and skin. Confusion. Convulsions. Dizziness. Headache. Nausea. Unconsciousness.	Use local exhaust or breathing protection.	Fresh air, rest. Artificial respiration may be needed. Refer for medical attention.
Skin	Redness.	Protective gloves. Protective clothing.	Remove contaminated clothes. Rinse and then wash skin with water and soap.
Eyes	Redness. Pain.	Wear safety goggles or eye protection in combination with breathing protection.	First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Ingestion	See Inhalation.	Do not eat, drink, or smoke during work. Wash hands before eating.	Rinse mouth. Give a slurry of activated charcoal in water to drink. Refer for medical attention .

SPILLAGE DISPOSAL	CLASSIFICATION & LABELLING
Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Do NOT let this chemical enter the environment. Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations.	According to UN GHS Criteria Transportation UN Classification UN Hazard Class: 6.1; UN Pack Group: III
STORAGE
Separated from food and feedstuffs. Well closed.
PACKAGING
Do not transport with food and feedstuffs.

o-PHENYLENEDIAMINE

ICSC: 1441

PHYSICAL & CHEMICAL INFORMATION
Physical State; Appearance BROWN-TO-YELLOW CRYSTALS. TURNS DARK ON EXPOSURE TO LIGHT. Physical dangers Dust explosion possible if in powder or granular form, mixed with air. Chemical dangers Decomposes on burning. This produces toxic fumes including nitrogen oxides.	Formula: C₆H₈N₂ / C₆H₄ (NH₂)₂ Molecular mass: 108.16 Boiling point: 256-258°C Melting point: 103-104°C Solubility in water, g/100ml at 35°C: 0.4 Vapour pressure, kPa at 20°C: 0.0013 Relative vapour density (air = 1): 3.73 Flash point: 156°C c.c. Explosive limits, vol% in air: 1.5-? Octanol/water partition coefficient as log Pow: 0.15 (calculated)

PHYSICAL & CHEMICAL INFORMATION

Physical State; Appearance
BROWN-TO-YELLOW CRYSTALS. TURNS DARK ON EXPOSURE TO LIGHT.

Physical dangers
Dust explosion possible if in powder or granular form, mixed with air.

Chemical dangers
Decomposes on burning. This produces toxic fumes including nitrogen oxides.

Formula: C₆H₈N₂ / C₆H₄ (NH₂)₂
Molecular mass: 108.16
Boiling point: 256-258°C
Melting point: 103-104°C
Solubility in water, g/100ml at 35°C: 0.4
Vapour pressure, kPa at 20°C: 0.0013
Relative vapour density (air = 1): 3.73
Flash point: 156°C c.c.
Explosive limits, vol% in air: 1.5-?
Octanol/water partition coefficient as log Pow: 0.15 (calculated)

EXPOSURE & HEALTH EFFECTS
Routes of exposure The substance can be absorbed into the body by inhalation and by ingestion. Effects of short-term exposure The substance is irritating to the eyes. The substance is mildly irritating to the skin and respiratory tract. The substance may cause effects on the blood. This may result in the formation of methaemoglobin. The effects may be delayed. Medical observation is indicated.	Inhalation risk A harmful contamination of the air will not or will only very slowly be reached on evaporation of this substance at 20°C; on spraying or dispersing, however, much faster. Effects of long-term or repeated exposure Repeated or prolonged contact may cause skin sensitization. The substance may have effects on the blood. This may result in anaemia. This substance is possibly carcinogenic to humans.

EXPOSURE & HEALTH EFFECTS

Routes of exposure
The substance can be absorbed into the body by inhalation and by ingestion.

Effects of short-term exposure
The substance is irritating to the eyes. The substance is mildly irritating to the skin and respiratory tract. The substance may cause effects on the blood. This may result in the formation of methaemoglobin. The effects may be delayed. Medical observation is indicated.

Inhalation risk
A harmful contamination of the air will not or will only very slowly be reached on evaporation of this substance at 20°C; on spraying or dispersing, however, much faster.

Effects of long-term or repeated exposure
Repeated or prolonged contact may cause skin sensitization. The substance may have effects on the blood. This may result in anaemia. This substance is possibly carcinogenic to humans.

OCCUPATIONAL EXPOSURE LIMITS
TLV: 0.1 mg/m³, as TWA; A3 (confirmed animal carcinogen with unknown relevance to humans). MAK: sensitization of skin (SH); carcinogen category: 3

ENVIRONMENT
The substance is very toxic to aquatic organisms. It is strongly advised not to let the chemical enter into the environment.

NOTES
Depending on the degree of exposure, periodic medical examination is suggested. Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available. See ICSCs 0805 and 1302.

ADDITIONAL INFORMATION

EC Classification
Symbol: T, N; R: 20/21-25-36-40-43-50/53-68; S: (1/2)-28-36/37-45-60-61; Note: C

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