ICSC 1437 - DESFLURANE

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DESFLURANE	ICSC: 1437 (May 2002)
1,2,2,2-tetrafluoroethyl difluoromethyl ether

CAS #: 57041-67-5

	ACUTE HAZARDS	PREVENTION	FIRE FIGHTING
FIRE & EXPLOSION	Not combustible. Gives off irritating or toxic fumes (or gases) in a fire.		In case of fire in the surroundings, use appropriate extinguishing media.


	SYMPTOMS	PREVENTION	FIRST AID
Inhalation	Cough. Sore throat. Dizziness. Drowsiness. Headache. Unconsciousness. See Notes.	Use ventilation, local exhaust or breathing protection.	Fresh air, rest. Artificial respiration may be needed. Refer for medical attention.
Skin	Dry skin. Redness.	Protective gloves.	Remove contaminated clothes. Rinse and then wash skin with water and soap.
Eyes	Redness. Pain.	Wear safety spectacles or eye protection in combination with breathing protection.	First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Ingestion	See Inhalation.	Do not eat, drink, or smoke during work.	Rinse mouth. Refer for medical attention .

SPILLAGE DISPOSAL	CLASSIFICATION & LABELLING
Personal protection: self-contained breathing apparatus. Ventilation. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations.	According to UN GHS Criteria Transportation UN Classification
STORAGE
Ventilation along the floor.
PACKAGING

DESFLURANE

ICSC: 1437

PHYSICAL & CHEMICAL INFORMATION
Physical State; Appearance COLOURLESS LIQUID. Physical dangers The vapour is heavier than air and may accumulate in lowered spaces causing a deficiency of oxygen. Chemical dangers Decomposes on contact with hot surfaces or flames. This produces corrosive gases such as hydrogen fluoride.	Formula: C₃H₂F₆O Molecular mass: 168 Boiling point: 23.5 °C Relative density (water = 1): 1.5 Solubility in water: poor Vapour pressure, kPa at 20°C: 89 Relative density of the vapour/air-mixture at 20°C (air = 1): 1.4

PHYSICAL & CHEMICAL INFORMATION

Physical State; Appearance
COLOURLESS LIQUID.

Physical dangers
The vapour is heavier than air and may accumulate in lowered spaces causing a deficiency of oxygen.

Chemical dangers
Decomposes on contact with hot surfaces or flames. This produces corrosive gases such as hydrogen fluoride.

Formula: C₃H₂F₆O
Molecular mass: 168
Boiling point: 23.5 °C
Relative density (water = 1): 1.5
Solubility in water: poor
Vapour pressure, kPa at 20°C: 89
Relative density of the vapour/air-mixture at 20°C (air = 1): 1.4

EXPOSURE & HEALTH EFFECTS
Routes of exposure The substance can be absorbed into the body by inhalation of its vapour and by ingestion. Effects of short-term exposure The substance is irritating to the eyes and skin. The vapour is irritating to the respiratory tract. The substance may cause effects on the central nervous system and cardiovascular system. Exposure at high levels could cause unconsciousness.	Inhalation risk A harmful contamination of the air can be reached very quickly on evaporation of this substance at 20°C. Effects of long-term or repeated exposure

EXPOSURE & HEALTH EFFECTS

Routes of exposure
The substance can be absorbed into the body by inhalation of its vapour and by ingestion.

Effects of short-term exposure
The substance is irritating to the eyes and skin. The vapour is irritating to the respiratory tract. The substance may cause effects on the central nervous system and cardiovascular system. Exposure at high levels could cause unconsciousness.

Inhalation risk
A harmful contamination of the air can be reached very quickly on evaporation of this substance at 20°C.

Effects of long-term or repeated exposure

OCCUPATIONAL EXPOSURE LIMITS
MAK: 4.8 mg/m³, 0.5 ppm; peak limitation category: II(2); skin absorption (H)

ENVIRONMENT

NOTES
Check oxygen content before entering area. High concentrations in the air cause a deficiency of oxygen with the risk of unconsciousness or death.

ADDITIONAL INFORMATION

EC Classification

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