ICSC 1017 - BRUCINE, ANHYDROUS

« back to the search result list

BRUCINE, ANHYDROUS	ICSC: 1017 (June 2002)
10,11-Dimethoxystrychnine 2,3-Dimethoxystrychnidin-10-one 2,3-Dimethylstrychnine Dimethoxystrychnine

CAS #: 357-57-3

UN #: 1570

EC Number: 206-614-7

	ACUTE HAZARDS	PREVENTION	FIRE FIGHTING
FIRE & EXPLOSION	Combustible. Gives off irritating or toxic fumes (or gases) in a fire.	NO open flames.	Use water spray, powder, foam, carbon dioxide.

STRICT HYGIENE! IN ALL CASES CONSULT A DOCTOR!
	SYMPTOMS	PREVENTION	FIRST AID
Inhalation	See Ingestion.	Use ventilation (not if powder), local exhaust or breathing protection.	Fresh air, rest. Artificial respiration may be needed. Refer for medical attention.
Skin		Protective gloves.	Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention .
Eyes	Redness.	Wear safety goggles.	First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Ingestion	Headache. Nausea. Vomiting. Muscle twitching. Restlessness. Convulsions. Laboured breathing.	Do not eat, drink, or smoke during work. Wash hands before eating.	Rinse mouth. Give a slurry of activated charcoal in water to drink. Refer for medical attention . Avoid unnecessary stimulation of the victim.

SPILLAGE DISPOSAL	CLASSIFICATION & LABELLING
Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Do NOT let this chemical enter the environment. Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations.	According to UN GHS Criteria Transportation UN Classification UN Hazard Class: 6.1; UN Pack Group: I
STORAGE
Separated from strong oxidants and food and feedstuffs. Dry. Well closed.
PACKAGING
Do not transport with food and feedstuffs.

BRUCINE, ANHYDROUS

ICSC: 1017

PHYSICAL & CHEMICAL INFORMATION
Physical State; Appearance COLOURLESS CRYSTALS OR WHITE CRYSTALLINE POWDER. Physical dangers Chemical dangers Decomposes on heating. This produces toxic fumes including nitrogen oxides. The solution in water is a weak base. Reacts with strong oxidants. This generates fire and explosion hazard.	Formula: C₂₃H₂₆N₂O₄ Molecular mass: 394.47 Boiling point: 470°C Melting point: 178°C Solubility in water: poor Octanol/water partition coefficient as log Pow: 0.98

PHYSICAL & CHEMICAL INFORMATION

Physical State; Appearance
COLOURLESS CRYSTALS OR WHITE CRYSTALLINE POWDER.

Physical dangers

Chemical dangers
Decomposes on heating. This produces toxic fumes including nitrogen oxides. The solution in water is a weak base. Reacts with strong oxidants. This generates fire and explosion hazard.

Formula: C₂₃H₂₆N₂O₄
Molecular mass: 394.47
Boiling point: 470°C
Melting point: 178°C
Solubility in water: poor
Octanol/water partition coefficient as log Pow: 0.98

EXPOSURE & HEALTH EFFECTS
Routes of exposure The substance can be absorbed into the body by inhalation of its aerosol and by ingestion. Effects of short-term exposure May cause mechanical irritation. The substance may cause effects on the nervous system and eyes. This may result in convulsions and respiratory paralysis. Exposure could cause death.	Inhalation risk Evaporation at 20°C is negligible; a harmful concentration of airborne particles can, however, be reached quickly when dispersed, especially if powdered. Effects of long-term or repeated exposure

EXPOSURE & HEALTH EFFECTS

Routes of exposure
The substance can be absorbed into the body by inhalation of its aerosol and by ingestion.

Effects of short-term exposure
May cause mechanical irritation. The substance may cause effects on the nervous system and eyes. This may result in convulsions and respiratory paralysis. Exposure could cause death.

Inhalation risk
Evaporation at 20°C is negligible; a harmful concentration of airborne particles can, however, be reached quickly when dispersed, especially if powdered.

Effects of long-term or repeated exposure

OCCUPATIONAL EXPOSURE LIMITS

ENVIRONMENT
The substance is harmful to aquatic organisms. This substance may be hazardous to the environment. Special attention should be given to birds.

NOTES
Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available. The recommendations on this Card also apply to Brucine hydrate (CAS 5892-11-5).

ADDITIONAL INFORMATION

EC Classification
Symbol: T+; R: 26/28-52/53; S: (1/2)-13-45-61

All rights reserved. The published material is being distributed without warranty of any kind, either expressed or implied. Neither ILO nor WHO nor the European Commission shall be responsible for the interpretation and use of the information contained in this material.