ICSC 0851 - CHLORPYRIFOS

« back to the search result list

CHLORPYRIFOS	ICSC: 0851 (April 2014)
O,O-Diethyl-O-3,5,6-trichloro-2-pyridyl phosphorothioate O,O-Diethyl O-(3,5,6-trichloro-2-pyridinyl) phosphorothioic acid ester Chlorpyrifos-ethyl

CAS #: 2921-88-2

UN #: 2783

EC Number: 220-864-4

	ACUTE HAZARDS	PREVENTION	FIRE FIGHTING
FIRE & EXPLOSION	Combustible. Gives off irritating or toxic fumes (or gases) in a fire. Liquid formulations containing organic solvents may be flammable. Risk of fire and explosion if formulations contain flammable/explosive solvents.	NO open flames.	Use water spray, foam, powder, carbon dioxide. In case of fire: keep drums, etc., cool by spraying with water.

STRICT HYGIENE! AVOID EXPOSURE OF ADOLESCENTS AND CHILDREN! IN ALL CASES CONSULT A DOCTOR! FIRST AID: USE PERSONAL PROTECTION.
	SYMPTOMS	PREVENTION	FIRST AID
Inhalation	Pupillary constriction, muscle cramp, excessive salivation. Muscle twitching. Convulsions. Dizziness. Sweating. Wheezing. Laboured breathing. Unconsciousness.	Use local exhaust or breathing protection.	Fresh air, rest. Refer immediately for medical attention. See Notes.
Skin	MAY BE ABSORBED! See Inhalation.	Protective gloves. Protective clothing.	Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer immediately for medical attention. See Notes.
Eyes	Redness. Pain. Pupillary constriction. Blurred vision.	Wear face shield or eye protection in combination with breathing protection if powder.	Rinse with plenty of water (remove contact lenses if easily possible). Refer for medical attention.
Ingestion	Excessive salivation. Nausea. Vomiting. Abdominal cramps. Diarrhoea. Further see Inhalation.	Do not eat, drink, or smoke during work. Wash hands before eating.	Rinse mouth. Do NOT induce vomiting. Refer immediately for medical attention. See Notes.

SPILLAGE DISPOSAL	CLASSIFICATION & LABELLING
Evacuate danger area! Consult an expert! Personal protection: chemical protection suit including self-contained breathing apparatus. Do NOT let this chemical enter the environment. Do NOT wash away into sewer. Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations.	According to UN GHS Criteria DANGER Toxic if swallowed, in contact with skin or if inhaled Causes damage to nervous system Causes damage to the nervous system through prolonged or repeated exposure Very toxic to aquatic life with long lasting effects Transportation UN Classification UN Hazard Class: 6.1; UN Pack Group: III
STORAGE
Store only in original container. Keep in a well-ventilated room. Separated from food and feedstuffs. Provision to contain effluent from fire extinguishing. Store in an area without drain or sewer access.
PACKAGING
Do not transport with food and feedstuffs. Marine pollutant.

CHLORPYRIFOS

ICSC: 0851

PHYSICAL & CHEMICAL INFORMATION
Physical State; Appearance COLOURLESS-TO-WHITE CRYSTALS WITH CHARACTERISTIC ODOUR. Physical dangers Chemical dangers Decomposes at 160°C. This produces toxic and corrosive fumes including hydrogen chloride, phosgene, phosphorus oxides, nitrogen oxides and sulfur oxides. Attacks copper and brass.	Formula: C₉H₁₁Cl₃NO₃PS Molecular mass: 350.6 Boiling point: No boiling point at normal pressure; decomposes at 160°C Melting point: 41-42°C Density: 1.4 g/cm³ Solubility in water, mg/l at 25°C: 1.4 (very poor) Vapour pressure, Pa at 25°C: 0.0024 Octanol/water partition coefficient as log Pow: 4.96

PHYSICAL & CHEMICAL INFORMATION

Physical State; Appearance
COLOURLESS-TO-WHITE CRYSTALS WITH CHARACTERISTIC ODOUR.

Physical dangers

Chemical dangers
Decomposes at 160°C. This produces toxic and corrosive fumes including hydrogen chloride, phosgene, phosphorus oxides, nitrogen oxides and sulfur oxides. Attacks copper and brass.

Formula: C₉H₁₁Cl₃NO₃PS
Molecular mass: 350.6
Boiling point: No boiling point at normal pressure; decomposes at 160°C
Melting point: 41-42°C
Density: 1.4 g/cm³
Solubility in water, mg/l at 25°C: 1.4 (very poor)
Vapour pressure, Pa at 25°C: 0.0024
Octanol/water partition coefficient as log Pow: 4.96

EXPOSURE & HEALTH EFFECTS
Routes of exposure The substance can be absorbed into the body by inhalation, through the skin and by ingestion. Effects of short-term exposure The substance may cause effects on the nervous system by a cholinesterase inhibiting effect. Exposure far above the OEL could cause death. The effects may be delayed. Medical observation is indicated.	Inhalation risk A harmful concentration of airborne particles can be reached quickly on spraying or when dispersed, especially if powdered. Effects of long-term or repeated exposure Cholinesterase inhibition. Cumulative effects are possible. See Acute Hazards/Symptoms.

EXPOSURE & HEALTH EFFECTS

Routes of exposure
The substance can be absorbed into the body by inhalation, through the skin and by ingestion.

Effects of short-term exposure
The substance may cause effects on the nervous system by a cholinesterase inhibiting effect. Exposure far above the OEL could cause death. The effects may be delayed. Medical observation is indicated.

Inhalation risk
A harmful concentration of airborne particles can be reached quickly on spraying or when dispersed, especially if powdered.

Effects of long-term or repeated exposure
Cholinesterase inhibition. Cumulative effects are possible. See Acute Hazards/Symptoms.

OCCUPATIONAL EXPOSURE LIMITS
TLV: 0.1 mg/m³, as TWA; (skin); A4 (not classifiable as a human carcinogen); BEI issued

ENVIRONMENT
The substance is very toxic to aquatic organisms. This substance may be hazardous to the environment. Special attention should be given to birds and bees. Bioaccumulation of this chemical may occur along the food chain, for example in fish and algae. The substance may cause long-term effects in the aquatic environment. This substance does enter the environment under normal use. Great care, however, should be taken to avoid any additional release, for example through inappropriate disposal.

ENVIRONMENT

The substance is very toxic to aquatic organisms. This substance may be hazardous to the environment. Special attention should be given to birds and bees. Bioaccumulation of this chemical may occur along the food chain, for example in fish and algae. The substance may cause long-term effects in the aquatic environment. This substance does enter the environment under normal use. Great care, however, should be taken to avoid any additional release, for example through inappropriate disposal.

NOTES
Do NOT take working clothes home. Do NOT use in the vicinity of a fire or a hot surface, or during welding. Depending on the degree of exposure, periodic medical examination is suggested. Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available. Following the disappearance of symptoms from a short-term exposure, delayed effects could become manifest (after several days or weeks). If the substance is formulated with solvent(s) also consult the card(s) (ICSC) of the solvent(s). Carrier solvents used in commercial formulations may change physical and toxicological properties.

NOTES

Do NOT take working clothes home.
Do NOT use in the vicinity of a fire or a hot surface, or during welding.
Depending on the degree of exposure, periodic medical examination is suggested.
Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available.
Following the disappearance of symptoms from a short-term exposure, delayed effects could become manifest (after several days or weeks).
If the substance is formulated with solvent(s) also consult the card(s) (ICSC) of the solvent(s).
Carrier solvents used in commercial formulations may change physical and toxicological properties.

ADDITIONAL INFORMATION

EC Classification
Symbol: T, N; R: 25-50/53; S: (1/2)-45-60-61

All rights reserved. The published material is being distributed without warranty of any kind, either expressed or implied. Neither ILO nor WHO nor the European Commission shall be responsible for the interpretation and use of the information contained in this material.