ICSC 0600 - XYLIDINE (MIXED ISOMERS)

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XYLIDINE (MIXED ISOMERS)	ICSC: 0600 (April 2007)
Dimethylaniline Aminodimethylbenzene Dimethylphenylamine

CAS #: 1300-73-8

UN #: 1711

EC Number: 215-091-4

	ACUTE HAZARDS	PREVENTION	FIRE FIGHTING
FIRE & EXPLOSION	Combustible. Gives off irritating or toxic fumes (or gases) in a fire. Above 90-98°C explosive vapour/air mixtures may be formed.	NO open flames. Above 90-98°C use a closed system and ventilation.	Use water spray, carbon dioxide, foam, powder.

AVOID ALL CONTACT!
	SYMPTOMS	PREVENTION	FIRST AID
Inhalation	Dizziness. Drowsiness. Headache. Nausea.	Use ventilation, local exhaust or breathing protection.	Fresh air, rest. Refer for medical attention.
Skin	MAY BE ABSORBED! See Ingestion.	Protective gloves. Protective clothing.	Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention .
Eyes		Wear safety spectacles or eye protection in combination with breathing protection.	Rinse with plenty of water for several minutes (remove contact lenses if easily possible).
Ingestion	Blue lips, fingernails and skin. Dizziness. Drowsiness. Headache. Nausea. Unconsciousness.	Do not eat, drink, or smoke during work.	Rinse mouth. Refer for medical attention .

SPILLAGE DISPOSAL	CLASSIFICATION & LABELLING
Personal protection: chemical protection suit and filter respirator for organic gases and vapours adapted to the airborne concentration of the substance. Do NOT let this chemical enter the environment. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations.	According to UN GHS Criteria WARNING Combustible liquid Harmful if swallowed or in contact with skin Suspected of causing cancer May cause drowsiness and dizziness May cause damage to blood May cause damage to blood, liver and kidneys through prolonged or repeated exposure Transportation UN Classification UN Hazard Class: 6.1; UN Pack Group: II
STORAGE
Separated from strong oxidants, acids, acid anhydrides, acid chlorides, hypochlorites, halogens and food and feedstuffs. Well closed. Store in an area without drain or sewer access.
PACKAGING
Do not transport with food and feedstuffs.

XYLIDINE (MIXED ISOMERS)

ICSC: 0600

PHYSICAL & CHEMICAL INFORMATION
Physical State; Appearance PALE YELLOW-TO-BROWN LIQUID WITH CHARACTERISTIC ODOUR. TURNS BROWN ON EXPOSURE TO AIR. Physical dangers Chemical dangers Decomposes on burning. This produces toxic and corrosive fumes including nitrogen oxides. Reacts violently with strong oxidants. Reacts with hypochlorites. This produces explosive chloroamines. Reacts with acids, acid anhydrides, acid chlorides and halogens. Attacks plastic and rubber.	Formula: C₈H₁₁N / (CH₃)₂C₆H₃NH₂ Molecular mass: 121.2 Boiling point: 216-228°C Relative density (water = 1): 0.97-1.07 Solubility in water: poor Vapour pressure, Pa at 20°C: <20 Relative vapour density (air = 1): 4.2 Relative density of the vapour/air-mixture at 20°C (air = 1): 1.00 Flash point: 90-98°C c.c. Auto-ignition temperature: 520-590°C Explosive limits, vol% in air: 1-7 Octanol/water partition coefficient as log Pow: 1.8-2.2 (estimated)

PHYSICAL & CHEMICAL INFORMATION

Physical State; Appearance
PALE YELLOW-TO-BROWN LIQUID WITH CHARACTERISTIC ODOUR. TURNS BROWN ON EXPOSURE TO AIR.

Physical dangers

Chemical dangers
Decomposes on burning. This produces toxic and corrosive fumes including nitrogen oxides. Reacts violently with strong oxidants. Reacts with hypochlorites. This produces explosive chloroamines. Reacts with acids, acid anhydrides, acid chlorides and halogens. Attacks plastic and rubber.

Formula: C₈H₁₁N / (CH₃)₂C₆H₃NH₂
Molecular mass: 121.2
Boiling point: 216-228°C
Relative density (water = 1): 0.97-1.07
Solubility in water: poor
Vapour pressure, Pa at 20°C: <20
Relative vapour density (air = 1): 4.2
Relative density of the vapour/air-mixture at 20°C (air = 1): 1.00
Flash point: 90-98°C c.c.
Auto-ignition temperature: 520-590°C
Explosive limits, vol% in air: 1-7
Octanol/water partition coefficient as log Pow: 1.8-2.2 (estimated)

EXPOSURE & HEALTH EFFECTS
Routes of exposure The substance can be absorbed into the body in hazardous amounts by inhalation, through the skin and by ingestion. Effects of short-term exposure Exposure at high levels could cause lowering of consciousness. Exposure at high levels could cause formation of methaemoglobin. The effects may be delayed. Medical observation is indicated.	Inhalation risk A harmful contamination of the air will be reached slowly on evaporation of this substance at 20°C; on spraying or dispersing, however, much faster. Effects of long-term or repeated exposure The substance may have effects on the blood. This may result in anaemia. The substance may have effects on the kidneys and liver. This substance is possibly carcinogenic to humans.

EXPOSURE & HEALTH EFFECTS

Routes of exposure
The substance can be absorbed into the body in hazardous amounts by inhalation, through the skin and by ingestion.

Effects of short-term exposure
Exposure at high levels could cause lowering of consciousness. Exposure at high levels could cause formation of methaemoglobin. The effects may be delayed. Medical observation is indicated.

Inhalation risk
A harmful contamination of the air will be reached slowly on evaporation of this substance at 20°C; on spraying or dispersing, however, much faster.

Effects of long-term or repeated exposure
The substance may have effects on the blood. This may result in anaemia. The substance may have effects on the kidneys and liver. This substance is possibly carcinogenic to humans.

OCCUPATIONAL EXPOSURE LIMITS
TLV: 0.5 ppm as TWA; (skin); BEI issued; A3 (confirmed animal carcinogen with unknown relevance to humans). MAK: skin absorption (H); carcinogen category: 3

ENVIRONMENT
This substance may be hazardous to the environment. Special attention should be given to aquatic organisms.

NOTES
Depending on the degree of exposure, periodic medical examination is suggested. Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available. Commercial xylidine is a mixture of isomers where the 2,4-, 2,5- and 2,6-isomers dominate. See ICSCs 0453, 1519, 1562, 1686 and 1687.

ADDITIONAL INFORMATION

EC Classification
Symbol: T, N; R: 23/24/25-33-51/53; S: (1/2)-28-36/37-45-61; Note: C

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