ICSC 0570 - DIETHYL SULFATE

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DIETHYL SULFATE	ICSC: 0570 (April 2013)
Sulfuric acid diethyl ester DES

CAS #: 64-67-5

UN #: 1594

EC Number: 200-589-6

	ACUTE HAZARDS	PREVENTION	FIRE FIGHTING
FIRE & EXPLOSION	Combustible. Gives off irritating or toxic fumes (or gases) in a fire.	NO open flames. See Chemical Dangers.	Use water spray, powder, foam, carbon dioxide.

AVOID ALL CONTACT! IN ALL CASES CONSULT A DOCTOR!
	SYMPTOMS	PREVENTION	FIRST AID
Inhalation	Cough. Sore throat. Laboured breathing. Shortness of breath. Symptoms may be delayed. See Notes.	Use ventilation, local exhaust or breathing protection.	Fresh air, rest. Half-upright position. Refer immediately for medical attention.
Skin	Redness. Pain. Serious skin burns.	Protective gloves. Protective clothing.	Remove contaminated clothes. Rinse skin with plenty of water or shower for at least 15 minutes. Refer immediately for medical attention.
Eyes	Redness. Pain. Severe burns.	Wear face shield or eye protection in combination with breathing protection.	First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Ingestion	Burns in mouth and throat. Burning sensation behind the breastbone. Abdominal pain. Shock or collapse.	Do not eat, drink, or smoke during work.	Rinse mouth. Do NOT induce vomiting. Give nothing to drink. Refer immediately for medical attention.

SPILLAGE DISPOSAL	CLASSIFICATION & LABELLING
Personal protection: complete protective clothing including self-contained breathing apparatus. Do NOT let this chemical enter the environment. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations.	According to UN GHS Criteria Toxic in contact with skin or if inhaled Harmful if swallowed Causes severe skin burns and eye damage May cause genetic defects May cause cancer Transportation UN Classification UN Hazard Class: 6.1; UN Pack Group: II
STORAGE
Separated from food and feedstuffs. Dry. Well closed. Keep in a well-ventilated room. Store in an area without drain or sewer access.
PACKAGING
Do not transport with food and feedstuffs.

DIETHYL SULFATE

ICSC: 0570

PHYSICAL & CHEMICAL INFORMATION
Physical State; Appearance OILY COLOURLESS LIQUID WITH CHARACTERISTIC ODOUR. TURNS BROWN ON EXPOSURE TO AIR. Physical dangers Chemical dangers Decomposes on heating. This produces flammable and toxic fumes. Reacts violently with ammonia, strong oxidants, strong bases and powdered metals. This generates fire hazard. Reacts with water and moisture. This produces sulfuric acid and ethanol.	Formula: C₄H₁₀O₄S / (C₂H₅)₂SO₄ Molecular mass: 154.2 Decomposes at 209°C Melting point: -25°C Relative density (water = 1): 1.2 Solubility in water: reaction Vapour pressure, Pa at 20°C: 20 Relative vapour density (air = 1): 5.3 Relative density of the vapour/air-mixture at 20°C (air = 1): 1.001 Flash point: 104°C c.c. Auto-ignition temperature: 360°C Explosive limits, vol% in air: 1.8-12.2 Octanol/water partition coefficient as log Pow: 1.14

PHYSICAL & CHEMICAL INFORMATION

Physical State; Appearance
OILY COLOURLESS LIQUID WITH CHARACTERISTIC ODOUR. TURNS BROWN ON EXPOSURE TO AIR.

Physical dangers

Chemical dangers
Decomposes on heating. This produces flammable and toxic fumes. Reacts violently with ammonia, strong oxidants, strong bases and powdered metals. This generates fire hazard. Reacts with water and moisture. This produces sulfuric acid and ethanol.

Formula: C₄H₁₀O₄S / (C₂H₅)₂SO₄
Molecular mass: 154.2
Decomposes at 209°C
Melting point: -25°C
Relative density (water = 1): 1.2
Solubility in water: reaction
Vapour pressure, Pa at 20°C: 20
Relative vapour density (air = 1): 5.3
Relative density of the vapour/air-mixture at 20°C (air = 1): 1.001
Flash point: 104°C c.c.
Auto-ignition temperature: 360°C
Explosive limits, vol% in air: 1.8-12.2
Octanol/water partition coefficient as log Pow: 1.14

EXPOSURE & HEALTH EFFECTS
Routes of exposure The substance can be absorbed into the body by inhalation, by ingestion and through the skin. Effects of short-term exposure The substance is corrosive to the eyes, skin and respiratory tract. Inhalation may cause lung oedema. See Notes. The effects may be delayed. Medical observation is indicated.	Inhalation risk No indication can be given about the rate at which a harmful concentration of this substance in the air is reached. Effects of long-term or repeated exposure This substance is probably carcinogenic to humans. May cause heritable genetic damage to human germ cells.

EXPOSURE & HEALTH EFFECTS

Routes of exposure
The substance can be absorbed into the body by inhalation, by ingestion and through the skin.

Effects of short-term exposure
The substance is corrosive to the eyes, skin and respiratory tract. Inhalation may cause lung oedema. See Notes. The effects may be delayed. Medical observation is indicated.

Inhalation risk
No indication can be given about the rate at which a harmful concentration of this substance in the air is reached.

Effects of long-term or repeated exposure
This substance is probably carcinogenic to humans. May cause heritable genetic damage to human germ cells.

OCCUPATIONAL EXPOSURE LIMITS
MAK: skin absorption (H); carcinogen category: 2; germ cell mutagen group: 2

ENVIRONMENT
The substance is harmful to aquatic organisms.

NOTES
The symptoms of lung oedema often do not become manifest until a few hours have passed and they are aggravated by physical effort. Rest and medical observation are therefore essential.

ADDITIONAL INFORMATION

EC Classification
Symbol: T; R: 45-46-20/21/22-34; S: 53-45; Note: E

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