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NICOTINE SULFATEICSC: 0520 (November 2023)
3-[(2S)-1-methylpyrrolidin-2-yl]pyridine;sulfuric acid
(-)-1-Methyl-2-(3-pyridyl)-pyrrolidine sulfate
(S)-3-(1-Methyl-2-pyrrolidinyl)-pyridine sulfate
3-(1-Methyl-2-pyrrolidinyl)-pyridine sulfate
CAS #: 65-30-5
UN #: 1658
EC Number: 200-606-7

  ACUTE HAZARDS PREVENTION FIRE FIGHTING
FIRE & EXPLOSION Not combustible. Gives off irritating or toxic fumes (or gases) in a fire.    NO open flames.    Use water spray, powder, alcohol-resistant foam, carbon dioxide.   

 PREVENT DISPERSION OF DUST! STRICT HYGIENE!  
  SYMPTOMS PREVENTION FIRST AID
Inhalation Cough.  Use local exhaust, ventilation and breathing protection.  Fresh air, rest. Refer for medical attention. 
Skin   Protective gloves. Protective clothing.  Remove contaminated clothes. Rinse skin with plenty of water or shower. Refer for medical attention . 
Eyes Redness.  Wear face shield or eye protection in combination with breathing protection if powder.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion Burning sensation. Confusion. Nausea. Vomiting. Excessive salivation. Diarrhoea. Sweating. Dizziness. Convulsions. Drowsiness. Respiratory arrest.  Do not eat, drink, or smoke during work. Wash hands before eating.  Rinse mouth. Give a slurry of activated charcoal in water to drink, but NOT if convulsions occur. Refer immediately for medical attention. 

SPILLAGE DISPOSAL CLASSIFICATION & LABELLING
Personal protection: complete protective clothing and particulate filter respirator adapted to the airborne concentration of the substance. Do NOT wash away into sewer. If appropriate, moisten first to prevent dusting. Sweep spilled substance into covered containers. Then store and dispose of according to local regulations. 

According to UN GHS Criteria

skull;toxiccancer;health hazenviro;aqua
DANGER
Fatal if swallowed
May cause damage to central nervous system and cardiovascular system
Toxic to aquatic life with long lasting effects 

Transportation
UN Classification
UN Hazard Class: 6.1; UN Pack Group: II 

STORAGE
Separated from strong oxidants and food and feedstuffs. Store in an area without drain or sewer access. Provision to contain effluent from fire extinguishing. 
PACKAGING
Do not transport with food and feedstuffs.
Put breakable packaging into closed unbreakable container. 
NICOTINE SULFATE ICSC: 0520
PHYSICAL & CHEMICAL INFORMATION

Physical State; Appearance
COLOURLESS CRYSTALS. 

Physical dangers
 

Chemical dangers
Decomposes on heating. This produces toxic fumes of sulfur oxides and nitrogen oxides. Reacts violently with strong oxidants. This generates explosion hazard. 

Formula: C20H26N4.O4S
Molecular mass: 418.6
Relative density (water = 1): 1.15
Solubility in water: soluble 


EXPOSURE & HEALTH EFFECTS

Routes of exposure
The substance can be absorbed into the body by inhalation of its aerosol and by ingestion. 

Effects of short-term exposure
The substance is irritating to the eyes and skin. The substance may cause effects on the central nervous system and cardiovascular system. This may result in central nervous system depression and respiratory depression. The effects may be delayed. Medical observation is indicated. 

Inhalation risk
Evaporation at 20°C is negligible; a harmful concentration of airborne particles can, however, be reached quickly on spraying or when dispersed, especially if powdered. 

Effects of long-term or repeated exposure
Animal tests show that this substance possibly causes toxic effects upon human reproduction. 


OCCUPATIONAL EXPOSURE LIMITS
TLV (see Notes).
EUL (see Notes) 

ENVIRONMENT
The substance is toxic to aquatic organisms. 

NOTES
See ICSC 0519. 

ADDITIONAL INFORMATION
  EC Classification
 

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