ICSC 0386 - 1,4-BENZENEDIAMINE DIHYDROCHLORIDE

« back to the search result list

1,4-BENZENEDIAMINE DIHYDROCHLORIDE	ICSC: 0386 (October 1999)
1,4-Phenylenediamine dihydrochloride 1,4-Diaminobenzene dihydrochloride 4-Aminoaniline dihydrochloride p-Phenylenediamine dihydrochloride

CAS #: 624-18-0

UN #: 1673

EC Number: 210-834-9

	ACUTE HAZARDS	PREVENTION	FIRE FIGHTING
FIRE & EXPLOSION	Combustible. Gives off irritating or toxic fumes (or gases) in a fire. Finely dispersed particles form explosive mixtures in air.	NO open flames. Closed system, dust explosion-proof electrical equipment and lighting. Prevent deposition of dust.	Use water spray, foam, powder, carbon dioxide.

PREVENT DISPERSION OF DUST! STRICT HYGIENE!
	SYMPTOMS	PREVENTION	FIRST AID
Inhalation	Dizziness. Headache. Laboured breathing. Blue lips, fingernails and skin. Confusion. Convulsions. Nausea. Unconsciousness.	Use local exhaust or breathing protection.	Fresh air, rest. Refer for medical attention.
Skin		Protective gloves. Protective clothing.	Remove contaminated clothes. Rinse skin with plenty of water or shower. Refer for medical attention .
Eyes	Redness.	Wear safety goggles or eye protection in combination with breathing protection.	First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Ingestion	See Inhalation.	Do not eat, drink, or smoke during work.	Rinse mouth. Refer for medical attention . Induce vomiting (ONLY IN CONSCIOUS PERSONS!).

SPILLAGE DISPOSAL	CLASSIFICATION & LABELLING
Personal protection: chemical protection suit including self-contained breathing apparatus. Sweep spilled substance into covered containers. Carefully collect remainder. Then store and dispose of according to local regulations.	According to UN GHS Criteria Transportation UN Classification UN Hazard Class: 6.1; UN Pack Group: III
STORAGE
Separated from food and feedstuffs.
PACKAGING
Do not transport with food and feedstuffs.

1,4-BENZENEDIAMINE DIHYDROCHLORIDE

ICSC: 0386

PHYSICAL & CHEMICAL INFORMATION
Physical State; Appearance WHITE-TO-SLIGHTLY-REDDISH CRYSTALS. Physical dangers Dust explosion possible if in powder or granular form, mixed with air. Chemical dangers Decomposes on heating. This produces toxic and corrosive fumes of nitrogen oxides and hydrogen chloride.	Formula: C₆H₈N₂. 2HCl / C₆H₄(NH₂)₂ . 2HCl Molecular mass: 181.1 Melting point: 275°C Solubility in water: very good Relative vapour density (air = 1): 6.2

PHYSICAL & CHEMICAL INFORMATION

Physical State; Appearance
WHITE-TO-SLIGHTLY-REDDISH CRYSTALS.

Physical dangers
Dust explosion possible if in powder or granular form, mixed with air.

Chemical dangers
Decomposes on heating. This produces toxic and corrosive fumes of nitrogen oxides and hydrogen chloride.

Formula: C₆H₈N₂. 2HCl / C₆H₄(NH₂)₂ . 2HCl
Molecular mass: 181.1
Melting point: 275°C
Solubility in water: very good
Relative vapour density (air = 1): 6.2

EXPOSURE & HEALTH EFFECTS
Routes of exposure The substance can be absorbed into the body by inhalation, through the skin and by ingestion. Effects of short-term exposure The substance is irritating to the eyes. The substance may cause effects on the blood and kidneys. This may result in the formation of methaemoglobin and kidney impairment. Medical observation is indicated. The effects may be delayed.	Inhalation risk Evaporation at 20°C is negligible; a harmful concentration of airborne particles can, however, be reached quickly when dispersed. Effects of long-term or repeated exposure Repeated or prolonged contact may cause skin sensitization. Repeated or prolonged inhalation may cause asthma.

EXPOSURE & HEALTH EFFECTS

Routes of exposure
The substance can be absorbed into the body by inhalation, through the skin and by ingestion.

Effects of short-term exposure
The substance is irritating to the eyes. The substance may cause effects on the blood and kidneys. This may result in the formation of methaemoglobin and kidney impairment. Medical observation is indicated. The effects may be delayed.

Inhalation risk
Evaporation at 20°C is negligible; a harmful concentration of airborne particles can, however, be reached quickly when dispersed.

Effects of long-term or repeated exposure
Repeated or prolonged contact may cause skin sensitization. Repeated or prolonged inhalation may cause asthma.

OCCUPATIONAL EXPOSURE LIMITS
TLV: 0.1 mg/m³, as TWA; A4 (not classifiable as a human carcinogen). MAK: (inhalable fraction): 0.1 mg/m³; carcinogen category: 3; peak limitation category: II(2); pregnancy risk group: C; skin absorption (H); sensitization of skin (SH)

ENVIRONMENT

NOTES
Depending on the degree of exposure, periodic medical examination is suggested. The symptoms of asthma often do not become manifest until a few hours have passed and they are aggravated by physical effort. Rest and medical observation are therefore essential. Anyone who has shown symptoms of asthma due to this substance should avoid all further contact. Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available. See ICSC 0805.

NOTES

Depending on the degree of exposure, periodic medical examination is suggested.
The symptoms of asthma often do not become manifest until a few hours have passed and they are aggravated by physical effort. Rest and medical observation are therefore essential.
Anyone who has shown symptoms of asthma due to this substance should avoid all further contact.
Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available.
See ICSC 0805.

ADDITIONAL INFORMATION

EC Classification
Symbol: T, N; R: 23/24/25-36-43-50/53; S: (1/2)-28-36/37-45-60-61

All rights reserved. The published material is being distributed without warranty of any kind, either expressed or implied. Neither ILO nor WHO nor the European Commission shall be responsible for the interpretation and use of the information contained in this material.