ICSC 0235 - CHLOROACETIC ACID

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CHLOROACETIC ACID	ICSC: 0235 (November 2016)
Monochloroacetic acid Chloroethanoic acid MCA

CAS #: 79-11-8

UN #: 1751

EC Number: 201-178-4

	ACUTE HAZARDS	PREVENTION	FIRE FIGHTING
FIRE & EXPLOSION	Combustible. Gives off irritating or toxic fumes (or gases) in a fire.	NO open flames. NO contact with incompatible substances. See Chemical Dangers.	Use water spray, powder, alcohol-resistant foam, carbon dioxide. In case of fire: keep drums, etc., cool by spraying with water.

AVOID ALL CONTACT! IN ALL CASES CONSULT A DOCTOR! FIRST AID: USE PERSONAL PROTECTION. See Notes.
	SYMPTOMS	PREVENTION	FIRST AID
Inhalation	Sore throat. Cough. Shortness of breath. Burning sensation behind the breastbone. Laboured breathing. Symptoms may be delayed. See Notes. Further see Ingestion.	Use local exhaust or breathing protection.	Fresh air, rest. Half-upright position. Artificial respiration may be needed. Refer immediately for medical attention.
Skin	MAY BE ABSORBED! Redness. Pain. Skin burns. Further see Ingestion.	Protective gloves. Protective clothing.	Wear protective gloves when administering first aid. First rinse with plenty of water for at least 15 minutes, then remove contaminated clothes and rinse again. See Notes. Refer immediately for medical attention.
Eyes	Redness. Pain. Severe burns.	Wear face shield or eye protection in combination with breathing protection if powder.	Rinse with plenty of water for several minutes (remove contact lenses if easily possible). Refer immediately for medical attention.
Ingestion	Burns in mouth and throat. Abdominal pain. Vomiting. Diarrhoea. Convulsions. Shock or collapse. Unconsciousness.	Do not eat, drink, or smoke during work. Wash hands before eating.	Rinse mouth. Do NOT induce vomiting. Refer immediately for medical attention. See Notes.

SPILLAGE DISPOSAL	CLASSIFICATION & LABELLING
Evacuate danger area! Consult an expert! Personal protection: chemical protection suit including self-contained breathing apparatus. Do NOT let this chemical enter the environment. Do NOT wash away into sewer. Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations.	According to UN GHS Criteria DANGER May be corrosive to metals Toxic if swallowed or in contact with skin Causes severe skin burns and eye damage May cause respiratory irritation Causes damage to organs Very toxic to aquatic life Transportation UN Classification UN Hazard Class: 6.1; UN Subsidiary Risks: 8; UN Pack Group: II
STORAGE
Separated from incompatible materials and food and feedstuffs. See Chemical Dangers. Dry. Store only in original container. Well closed. Ventilation along the floor. Store in an area without drain or sewer access.
PACKAGING
Do not transport with food and feedstuffs.

CHLOROACETIC ACID

ICSC: 0235

PHYSICAL & CHEMICAL INFORMATION
Physical State; Appearance COLOURLESS HYGROSCOPIC CRYSTALS WITH PUNGENT ODOUR. Physical dangers The vapour is heavier than air. Chemical dangers Decomposes on burning. This produces toxic fumes including hydrogen chloride and phosgene. The solution in water is a medium strong acid. Attacks metals. This produces a combustible/explosive gas (hydrogen - see ICSC 0001). Reacts with bases, oxidizing substances and reducing agents. This produces toxic and flammable gases. This generates toxic, fire and explosion hazard. Attacks some forms of plastic, some forms of rubber and coatings.	Formula: C₂H₃ClO₂ / ClCH₂COOH Molecular mass: 94.5 Boiling point: 189°C Melting point: see Notes Density (at 20°C): 1.58 g/cm³ Solubility in water at 20°C: very good Vapour pressure, Pa at 25°C: < 10 Relative vapour density (air = 1): 3.3 Flash point: 126°C c.c. Auto-ignition temperature: 470°C Explosive limits, vol% in air: 8 -? Octanol/water partition coefficient as log Pow: 0.34

PHYSICAL & CHEMICAL INFORMATION

Physical State; Appearance
COLOURLESS HYGROSCOPIC CRYSTALS WITH PUNGENT ODOUR.

Physical dangers
The vapour is heavier than air.

Chemical dangers
Decomposes on burning. This produces toxic fumes including hydrogen chloride and phosgene. The solution in water is a medium strong acid. Attacks metals. This produces a combustible/explosive gas (hydrogen - see ICSC 0001). Reacts with bases, oxidizing substances and reducing agents. This produces toxic and flammable gases. This generates toxic, fire and explosion hazard. Attacks some forms of plastic, some forms of rubber and coatings.

Formula: C₂H₃ClO₂ / ClCH₂COOH
Molecular mass: 94.5
Boiling point: 189°C
Melting point: see Notes
Density (at 20°C): 1.58 g/cm³
Solubility in water at 20°C: very good
Vapour pressure, Pa at 25°C: < 10
Relative vapour density (air = 1): 3.3
Flash point: 126°C c.c.
Auto-ignition temperature: 470°C
Explosive limits, vol% in air: 8 -?
Octanol/water partition coefficient as log Pow: 0.34

EXPOSURE & HEALTH EFFECTS
Routes of exposure The substance can be absorbed into the body by inhalation, through the skin and by ingestion. Effects of short-term exposure The substance is corrosive to the eyes, skin and respiratory tract. Inhalation of high concentrations may cause lung oedema, but only after initial corrosive effects on the eyes and the upper respiratory tract have become manifest. See Notes. The substance may cause effects on the metabolism. This may result in metabolic acidosis and multiple organ failure. Exposure could cause death. The effects may be delayed. Medical observation is indicated.	Inhalation risk A harmful contamination of the air will be reached slowly on evaporation of this substance at 20°C. Effects of long-term or repeated exposure Repeated or prolonged inhalation may cause effects on the lungs.

EXPOSURE & HEALTH EFFECTS

Routes of exposure
The substance can be absorbed into the body by inhalation, through the skin and by ingestion.

Effects of short-term exposure
The substance is corrosive to the eyes, skin and respiratory tract. Inhalation of high concentrations may cause lung oedema, but only after initial corrosive effects on the eyes and the upper respiratory tract have become manifest. See Notes. The substance may cause effects on the metabolism. This may result in metabolic acidosis and multiple organ failure. Exposure could cause death. The effects may be delayed. Medical observation is indicated.

Inhalation risk
A harmful contamination of the air will be reached slowly on evaporation of this substance at 20°C.

Effects of long-term or repeated exposure
Repeated or prolonged inhalation may cause effects on the lungs.

OCCUPATIONAL EXPOSURE LIMITS
TLV: 0.5 ppm as TWA; (skin); A4 (not classifiable as a human carcinogen). MAK: 2.0 mg/m³, 0.5 ppm; peak limitation category: I(2); pregnancy risk group: C

ENVIRONMENT
The substance is very toxic to aquatic organisms.

NOTES
After skin contact, immediately rinsing with plenty of water is needed. Alternatively, emergency baths with 3 - 5 % sodium bicarbonate can be used to submerge the exposed skin. When > 5 % of the skin surface is affected a severe and even a life-threatening intoxication may occur. Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available. Consult a poison information centre or an expert for further information. The symptoms of lung oedema often do not become manifest until a few hours have passed and they are aggravated by physical effort. Rest and medical observation are therefore essential. Immediate administration of an appropriate inhalation therapy by a doctor, or by an authorized person, should be considered. Other melting points: 63°C (alpha form), 56.2°C (beta form), 52.5°C (gamma form). Other UN numbers: 1750 Chloroacetic acid, solution; 3250 Chloroacetic acid, molten.

NOTES

After skin contact, immediately rinsing with plenty of water is needed. Alternatively, emergency baths with 3 - 5 % sodium bicarbonate can be used to submerge the exposed skin.
When > 5 % of the skin surface is affected a severe and even a life-threatening intoxication may occur.
Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available.
Consult a poison information centre or an expert for further information.
The symptoms of lung oedema often do not become manifest until a few hours have passed and they are aggravated by physical effort. Rest and medical observation are therefore essential.
Immediate administration of an appropriate inhalation therapy by a doctor, or by an authorized person, should be considered.
Other melting points: 63°C (alpha form), 56.2°C (beta form), 52.5°C (gamma form).
Other UN numbers: 1750 Chloroacetic acid, solution; 3250 Chloroacetic acid, molten.

ADDITIONAL INFORMATION

EC Classification
Symbol: T, C, N; R: 23/24/25-34-50; S: (1/2)-26-36/37/39-45-61-63

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