ICSC 0197 - STRYCHNINE

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STRYCHNINE	ICSC: 0197 (December 2000)
Strychnidin-10-one

CAS #: 57-24-9

UN #: 1692

EC Number: 200-319-7

	ACUTE HAZARDS	PREVENTION	FIRE FIGHTING
FIRE & EXPLOSION	Not combustible. Gives off irritating or toxic fumes (or gases) in a fire.	NO contact with oxidizing agents.	In case of fire in the surroundings, use appropriate extinguishing media.

AVOID ALL CONTACT! IN ALL CASES CONSULT A DOCTOR!
	SYMPTOMS	PREVENTION	FIRST AID
Inhalation	See Ingestion.	Use local exhaust or breathing protection.	Fresh air, rest. Artificial respiration may be needed. Refer for medical attention.
Skin		Protective gloves.	Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention .
Eyes		Wear safety goggles.	First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Ingestion	Convulsions. Muscle stiffness. Shock or collapse.	Do not eat, drink, or smoke during work. Wash hands before eating.	Rinse mouth. Refer for medical attention . Avoid unnecessary stimulation of the victim.

SPILLAGE DISPOSAL	CLASSIFICATION & LABELLING
Personal protection: self-contained breathing apparatus. Do NOT let this chemical enter the environment. Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations.	According to UN GHS Criteria Transportation UN Classification UN Hazard Class: 6.1; UN Pack Group: I
STORAGE
Provision to contain effluent from fire extinguishing. Separated from strong oxidants and food and feedstuffs. Well closed.
PACKAGING
Do not transport with food and feedstuffs. Marine pollutant.

STRYCHNINE

ICSC: 0197

PHYSICAL & CHEMICAL INFORMATION
Physical State; Appearance ODOURLESS AND COLOURLESS CRYSTALS WITH BITTER TASTE. Physical dangers Chemical dangers Decomposes on heating. This produces toxic fumes including nitrogen oxides. The substance is a weak base. Reacts with strong oxidants. This generates fire and explosion hazard.	Formula: C₂₁H₂₂N₂O₂ Molecular mass: 334.4 Decomposes Melting point: 275-285°C Density: 1.36 g/cm³ Solubility in water: none Octanol/water partition coefficient as log Pow: 1.68

PHYSICAL & CHEMICAL INFORMATION

Physical State; Appearance
ODOURLESS AND COLOURLESS CRYSTALS WITH BITTER TASTE.

Physical dangers

Chemical dangers
Decomposes on heating. This produces toxic fumes including nitrogen oxides. The substance is a weak base. Reacts with strong oxidants. This generates fire and explosion hazard.

Formula: C₂₁H₂₂N₂O₂
Molecular mass: 334.4
Decomposes
Melting point: 275-285°C
Density: 1.36 g/cm³
Solubility in water: none
Octanol/water partition coefficient as log Pow: 1.68

EXPOSURE & HEALTH EFFECTS
Routes of exposure The substance can be absorbed into the body by inhalation of its aerosol and by ingestion. Effects of short-term exposure The substance may cause effects on the central nervous system. This may result in convulsions, muscle contractions and respiratory failure. Exposure could cause death.	Inhalation risk Evaporation at 20°C is negligible; a harmful concentration of airborne particles can, however, be reached quickly when dispersed, especially if powdered. Effects of long-term or repeated exposure

EXPOSURE & HEALTH EFFECTS

Routes of exposure
The substance can be absorbed into the body by inhalation of its aerosol and by ingestion.

Effects of short-term exposure
The substance may cause effects on the central nervous system. This may result in convulsions, muscle contractions and respiratory failure. Exposure could cause death.

Inhalation risk
Evaporation at 20°C is negligible; a harmful concentration of airborne particles can, however, be reached quickly when dispersed, especially if powdered.

Effects of long-term or repeated exposure

OCCUPATIONAL EXPOSURE LIMITS
TLV: 0.15 mg/m³, as TWA

ENVIRONMENT
The substance is very toxic to aquatic organisms. This substance may be hazardous to the environment. Special attention should be given to birds. This substance does enter the environment under normal use. Great care, however, should be taken to avoid any additional release, for example through inappropriate disposal.

NOTES
Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available.

ADDITIONAL INFORMATION

EC Classification
Symbol: T+, N; R: 27/28-50/53; S: (1/2)-36/37-45-60-61

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