ICSC 0191 - PROPOXUR

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PROPOXUR	ICSC: 0191 (April 2017)
2-Isopropoxyphenyl methylcarbamate Phenol, 2-(1-methylethoxy)-,methylcarbamate 2-(1-Methylethoxy)phenyl methylcarbamate PHC

CAS #: 114-26-1

UN #: 2757

EC Number: 204-043-8

	ACUTE HAZARDS	PREVENTION	FIRE FIGHTING
FIRE & EXPLOSION	Combustible under specific conditions. Liquid formulations containing organic solvents may be flammable. Gives off irritating or toxic fumes (or gases) in a fire.	NO open flames.	Use water spray, foam, powder, carbon dioxide.

PREVENT DISPERSION OF DUST! STRICT HYGIENE! AVOID EXPOSURE OF ADOLESCENTS AND CHILDREN! IN ALL CASES CONSULT A DOCTOR!
	SYMPTOMS	PREVENTION	FIRST AID
Inhalation	Blurred vision. Dizziness. Pupillary constriction, muscle cramp, excessive salivation. Sweating. Laboured breathing. Weakness. Headache. Abdominal cramps. Diarrhoea. Nausea. Vomiting. Muscle twitching. Convulsions. Unconsciousness.	Use local exhaust or breathing protection.	Fresh air, rest. Artificial respiration may be needed. Refer immediately for medical attention. See Notes.
Skin	MAY BE ABSORBED! Further see Inhalation.	Protective gloves. Protective clothing.	Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention .
Eyes		Wear safety spectacles or eye protection in combination with breathing protection if powder.	First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Ingestion	See Inhalation.	Do not eat, drink, or smoke during work. Wash hands before eating.	Give a slurry of activated charcoal in water to drink. Refer immediately for medical attention. See Notes.

SPILLAGE DISPOSAL	CLASSIFICATION & LABELLING
Personal protection: chemical protection suit including self-contained breathing apparatus. Do NOT let this chemical enter the environment. Sweep spilled substance into sealable containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations.	According to UN GHS Criteria DANGER Fatal if swallowed Toxic if inhaled Suspected of causing cancer Causes damage to nervous system Causes damage to the nervous system through prolonged or repeated exposure Very toxic to aquatic life with long lasting effects Transportation UN Classification UN Hazard Class: 6.1; UN Pack Group: II
STORAGE
Provision to contain effluent from fire extinguishing. Separated from food and feedstuffs. Keep in a well-ventilated room. Store only in original container. Store in an area without drain or sewer access.
PACKAGING
Do not transport with food and feedstuffs. Marine pollutant.

PROPOXUR

ICSC: 0191

PHYSICAL & CHEMICAL INFORMATION
Physical State; Appearance WHITE CRYSTALLINE POWDER. Physical dangers Chemical dangers Decomposes on heating and on burning. This produces toxic fumes including methyl isocyanate and nitrogen oxides.	Formula: C₁₁H₁₅NO₃ Molecular mass: 209.2 Decomposes: see Notes. Melting point: 91°C Density (at 20°C): 1.1 g/cm³ Solubility in water, g/100ml at 20°C: 0.2 (poor) Vapour pressure, Pa at 20°C: 0.001 Octanol/water partition coefficient as log Pow: 1.52

PHYSICAL & CHEMICAL INFORMATION

Physical State; Appearance
WHITE CRYSTALLINE POWDER.

Physical dangers

Chemical dangers
Decomposes on heating and on burning. This produces toxic fumes including methyl isocyanate and nitrogen oxides.

Formula: C₁₁H₁₅NO₃
Molecular mass: 209.2
Decomposes: see Notes.
Melting point: 91°C
Density (at 20°C): 1.1 g/cm³
Solubility in water, g/100ml at 20°C: 0.2 (poor)
Vapour pressure, Pa at 20°C: 0.001
Octanol/water partition coefficient as log Pow: 1.52

EXPOSURE & HEALTH EFFECTS
Routes of exposure The substance can be absorbed into the body by inhalation, through the skin and by ingestion. Effects of short-term exposure The substance may cause effects on the nervous system by a cholinesterase inhibiting effect. This may result in convulsions and respiratory depression. Exposure could cause death.	Inhalation risk A harmful concentration of airborne particles can be reached quickly on spraying or when dispersed, especially if powdered. Effects of long-term or repeated exposure Cholinesterase inhibition. Cumulative effects are possible. See Acute Hazards/Symptoms. Tumours have been detected in experimental animals but may not be relevant to humans.

EXPOSURE & HEALTH EFFECTS

Routes of exposure
The substance can be absorbed into the body by inhalation, through the skin and by ingestion.

Effects of short-term exposure
The substance may cause effects on the nervous system by a cholinesterase inhibiting effect. This may result in convulsions and respiratory depression. Exposure could cause death.

Inhalation risk
A harmful concentration of airborne particles can be reached quickly on spraying or when dispersed, especially if powdered.

Effects of long-term or repeated exposure
Cholinesterase inhibition. Cumulative effects are possible. See Acute Hazards/Symptoms. Tumours have been detected in experimental animals but may not be relevant to humans.

OCCUPATIONAL EXPOSURE LIMITS
TLV: 0.5 mg/m³, as TWA; A3 (confirmed animal carcinogen with unknown relevance to humans); BEI issued. MAK: (inhalable fraction): 2 mg/m³; peak limitation category: II(8)

ENVIRONMENT
The substance is very toxic to aquatic organisms. This substance may be hazardous to the environment. Special attention should be given to mammals, birds, soil organisms and bees. This substance does enter the environment under normal use. Great care, however, should be taken to avoid any additional release, for example through inappropriate disposal.

NOTES
Decomposition of compound starts at 220°C. Depending on the degree of exposure, periodic medical examination is suggested. Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available. If the substance is formulated with solvent(s) also consult the card(s) (ICSC) of the solvent(s). Carrier solvents used in commercial formulations may change physical and toxicological properties.

NOTES

Decomposition of compound starts at 220°C.
Depending on the degree of exposure, periodic medical examination is suggested.
Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available.
If the substance is formulated with solvent(s) also consult the card(s) (ICSC) of the solvent(s).
Carrier solvents used in commercial formulations may change physical and toxicological properties.

ADDITIONAL INFORMATION

EC Classification
Symbol: T, N; R: 25-50/53; S: (1/2)-37-45-60-61

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