ICSC 0053 - LINDANE

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LINDANE	ICSC: 0053 (November 2016)
gamma-1,2,3,4,5,6-Hexachlorocyclohexane gamma-BHC gamma-HCH

CAS #: 58-89-9

UN #: 2761

EC Number: 200-401-2

	ACUTE HAZARDS	PREVENTION	FIRE FIGHTING
FIRE & EXPLOSION	Not combustible. Liquid formulations containing organic solvents may be flammable. Gives off irritating or toxic fumes (or gases) in a fire. Risk of fire and explosion if formulations contain flammable/explosive solvents.		In case of fire in the surroundings, use appropriate extinguishing media. In case of fire: keep drums, etc., cool by spraying with water.

AVOID ALL CONTACT! AVOID EXPOSURE OF BREASTFEEDING WOMEN!
	SYMPTOMS	PREVENTION	FIRST AID
Inhalation	Cough. Sore throat. Further see Ingestion.	Avoid inhalation of dust.	Fresh air, rest. Refer for medical attention.
Skin	MAY BE ABSORBED!	Protective gloves. Protective clothing.	Wear protective gloves when administering first aid. Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention .
Eyes	Redness.	Wear face shield or eye protection in combination with breathing protection.	First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Ingestion	Nausea. Vomiting. Diarrhoea. Headache. Dizziness. Tremor. Convulsions.	Do not eat, drink, or smoke during work. Wash hands before eating.	Rinse mouth. Give a slurry of activated charcoal in water to drink, but NOT if convulsions occur. Refer immediately for medical attention. Rest.

SPILLAGE DISPOSAL	CLASSIFICATION & LABELLING
Personal protection: filter respirator for organic gases and particulates adapted to the airborne concentration of the substance, chemical protection suit including self-contained breathing apparatus and protective gloves. Do NOT let this chemical enter the environment. Sweep spilled substance into sealable non-metallic containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations.	According to UN GHS Criteria DANGER Toxic if swallowed or in contact with skin Harmful if inhaled May cause cancer May cause harm to breast-fed children Causes damage to the nervous system, the bone marrow and the liver through prolonged or repeated exposure Very toxic to aquatic life with long lasting effects Transportation UN Classification UN Hazard Class: 6.1; UN Pack Group: III
STORAGE
Well closed. Store in an area without drain or sewer access. Provision to contain effluent from fire extinguishing. Separated from bases and food and feedstuffs.
PACKAGING
Do not transport with food and feedstuffs. Severe marine pollutant.

LINDANE

ICSC: 0053

PHYSICAL & CHEMICAL INFORMATION
Physical State; Appearance WHITE CRYSTALLINE POWDER. Physical dangers No data. Chemical dangers Decomposes on heating and on burning. This produces toxic and corrosive fumes including chlorine (see ICSC 0126), hydrogen chloride (see ICSC 0163) and phosgene (see ICSC 0007). Reacts with bases. This produces toxic and corrosive fumes including hydrogen chloride and trichlorobenzenes (see ICSCs 0344, 1049 and 1222).	Formula: C₆H₆Cl₆ Molecular mass: 290.8 Boiling point: 323°C Melting point: 113°C Density: 1.9 g/cm³ Solubility in water, g/100ml at 20°C: 0.0007 (very poor) Vapour pressure, Pa at 20°C: 0.0012 Relative density of the vapour/air-mixture at 20°C (air = 1): 1 Octanol/water partition coefficient as log Pow: 3.61 - 3.72

PHYSICAL & CHEMICAL INFORMATION

Physical State; Appearance
WHITE CRYSTALLINE POWDER.

Physical dangers
No data.

Chemical dangers
Decomposes on heating and on burning. This produces toxic and corrosive fumes including chlorine (see ICSC 0126), hydrogen chloride (see ICSC 0163) and phosgene (see ICSC 0007). Reacts with bases. This produces toxic and corrosive fumes including hydrogen chloride and trichlorobenzenes (see ICSCs 0344, 1049 and 1222).

Formula: C₆H₆Cl₆
Molecular mass: 290.8
Boiling point: 323°C
Melting point: 113°C
Density: 1.9 g/cm³
Solubility in water, g/100ml at 20°C: 0.0007 (very poor)
Vapour pressure, Pa at 20°C: 0.0012
Relative density of the vapour/air-mixture at 20°C (air = 1): 1
Octanol/water partition coefficient as log Pow: 3.61 - 3.72

EXPOSURE & HEALTH EFFECTS
Routes of exposure The substance can be absorbed into the body by inhalation of its aerosol, through the skin and by ingestion. Effects of short-term exposure The substance may cause effects on the central nervous system. This may result in convulsions. Exposure could cause death. Medical observation is indicated.	Inhalation risk A harmful concentration of airborne particles can be reached quickly when dispersed. Effects of long-term or repeated exposure The substance may have effects on the nervous system, bone marrow and liver. This substance is carcinogenic to humans. Animal tests show that this substance possibly causes toxicity to human reproduction or development.

EXPOSURE & HEALTH EFFECTS

Routes of exposure
The substance can be absorbed into the body by inhalation of its aerosol, through the skin and by ingestion.

Effects of short-term exposure
The substance may cause effects on the central nervous system. This may result in convulsions. Exposure could cause death. Medical observation is indicated.

Inhalation risk
A harmful concentration of airborne particles can be reached quickly when dispersed.

Effects of long-term or repeated exposure
The substance may have effects on the nervous system, bone marrow and liver. This substance is carcinogenic to humans. Animal tests show that this substance possibly causes toxicity to human reproduction or development.

OCCUPATIONAL EXPOSURE LIMITS
TLV: 0.5 mg/m³, as TWA; (skin); A3 (confirmed animal carcinogen with unknown relevance to humans). MAK: (inhalable fraction): 0.1 mg/m³; peak limitation category: II(8); skin absorption (H); carcinogen category: 4; pregnancy risk group: C

ENVIRONMENT
The substance is very toxic to aquatic organisms. Bioaccumulation of this chemical may occur along the food chain, for example in fish and seafood. The substance may cause long-term effects in the aquatic environment. This substance does enter the environment under normal use. Great care, however, should be taken to avoid any additional release, for example through inappropriate disposal.

NOTES
Depending on the degree of exposure, periodic medical examination is suggested. Carrier solvents used in commercial formulations may change physical and toxicological properties. Do NOT take working clothes home. Do NOT use in the vicinity of a fire or a hot surface, or during welding. See ICSCs 0487, 0795 and 0796.

ADDITIONAL INFORMATION

EC Classification
Symbol: T, N; R: 20/21-25-48/22-64-50/53; S: (1/2)-36/37-45-60-61

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