ICSC 0037 - 1,4-DICHLOROBENZENE

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1,4-DICHLOROBENZENE	ICSC: 0037 (May 2018)
p-Dichlorobenzene PDCB

CAS #: 106-46-7

UN #: 3077

EC Number: 203-400-5

	ACUTE HAZARDS	PREVENTION	FIRE FIGHTING
FIRE & EXPLOSION	Combustible. Gives off irritating or toxic fumes (or gases) in a fire. Above 66°C explosive vapour/air mixtures may be formed. Finely dispersed particles form explosive mixtures in air.	NO open flames. Above 66°C use a closed system, ventilation and explosion-proof electrical equipment. Prevent deposition of dust.	Use water spray, powder, foam, carbon dioxide. In case of fire: keep drums, etc., cool by spraying with water.

PREVENT DISPERSION OF DUST! STRICT HYGIENE!
	SYMPTOMS	PREVENTION	FIRST AID
Inhalation	Cough. Sore throat. Drowsiness. Headache. Nausea. Shortness of breath. Vomiting.	Use ventilation, local exhaust or breathing protection.	Fresh air, rest. Refer for medical attention.
Skin		Protective gloves.	Remove contaminated clothes. Rinse and then wash skin with water and soap.
Eyes	Redness. Pain.	Wear safety goggles or eye protection in combination with breathing protection.	First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Ingestion	Diarrhoea. Further see Inhalation.	Do not eat, drink, or smoke during work.	Give one or two glasses of water to drink. Refer for medical attention .

SPILLAGE DISPOSAL	CLASSIFICATION & LABELLING
Personal protection: filter respirator for organic gases and particulates adapted to the airborne concentration of the substance. Do NOT let this chemical enter the environment. Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations.	According to UN GHS Criteria WARNING Harmful if swallowed Causes serious eye irritation Suspected of causing cancer Very toxic to aquatic life with long lasting effects Transportation UN Classification UN Hazard Class: 9; UN Pack Group: III
STORAGE
Separated from strong oxidants and food and feedstuffs. Provision to contain effluent from fire extinguishing. Keep in a well-ventilated room. Store in an area without drain or sewer access.
PACKAGING
Do not transport with food and feedstuffs. Marine pollutant.

1,4-DICHLOROBENZENE

ICSC: 0037

PHYSICAL & CHEMICAL INFORMATION
Physical State; Appearance COLOURLESS-TO-WHITE CRYSTALS WITH CHARACTERISTIC ODOUR. Physical dangers Dust explosion possible if in powder or granular form, mixed with air. Chemical dangers On combustion, forms toxic and corrosive fumes including hydrogen chloride (see ICSC 0163) and phosgene (see ICSC 0007). Upon heating, toxic fumes are formed. Reacts with strong oxidants. This generates fire and explosion hazard.	Formula: C₆H₄Cl₂ Molecular mass: 147 Boiling point: 174°C Melting point: 53°C Density: 1.2 g/cm³ Solubility in water, mg/l at 20°C: 49 (practically insoluble) Vapour pressure, Pa at 20°C: 170 Relative vapour density (air = 1): 5.08 Relative density of the vapour/air-mixture at 20°C (air = 1): 1.01 Flash point: 66°C c.c. Explosive limits, vol% in air: 1.7-5.9 Octanol/water partition coefficient as log Pow: 3.37 Auto-ignition temperature: 640°C Viscosity: 0.73 mPa*s at 70°C

PHYSICAL & CHEMICAL INFORMATION

Physical State; Appearance
COLOURLESS-TO-WHITE CRYSTALS WITH CHARACTERISTIC ODOUR.

Physical dangers
Dust explosion possible if in powder or granular form, mixed with air.

Chemical dangers
On combustion, forms toxic and corrosive fumes including hydrogen chloride (see ICSC 0163) and phosgene (see ICSC 0007). Upon heating, toxic fumes are formed. Reacts with strong oxidants. This generates fire and explosion hazard.

Formula: C₆H₄Cl₂
Molecular mass: 147
Boiling point: 174°C
Melting point: 53°C
Density: 1.2 g/cm³
Solubility in water, mg/l at 20°C: 49 (practically insoluble)
Vapour pressure, Pa at 20°C: 170
Relative vapour density (air = 1): 5.08
Relative density of the vapour/air-mixture at 20°C (air = 1): 1.01
Flash point: 66°C c.c.
Explosive limits, vol% in air: 1.7-5.9
Octanol/water partition coefficient as log Pow: 3.37
Auto-ignition temperature: 640°C
Viscosity: 0.73 mPa*s at 70°C

EXPOSURE & HEALTH EFFECTS
Routes of exposure The substance can be absorbed into the body by inhalation and by ingestion. Effects of short-term exposure The substance is irritating to the eyes, respiratory tract and skin. The substance may cause effects on the blood. This may result in haemolytic anaemia. The substance may cause effects on the central nervous system.	Inhalation risk A harmful contamination of the air will be reached rather slowly on evaporation of this substance at 20°C. Effects of long-term or repeated exposure The substance may have effects on the liver, central nervous system, blood and lungs. This may result in liver function impairment, neuropathy and anaemia. This substance is possibly carcinogenic to humans.

EXPOSURE & HEALTH EFFECTS

Routes of exposure
The substance can be absorbed into the body by inhalation and by ingestion.

Effects of short-term exposure
The substance is irritating to the eyes, respiratory tract and skin. The substance may cause effects on the blood. This may result in haemolytic anaemia. The substance may cause effects on the central nervous system.

Inhalation risk
A harmful contamination of the air will be reached rather slowly on evaporation of this substance at 20°C.

Effects of long-term or repeated exposure
The substance may have effects on the liver, central nervous system, blood and lungs. This may result in liver function impairment, neuropathy and anaemia. This substance is possibly carcinogenic to humans.

OCCUPATIONAL EXPOSURE LIMITS
TLV: 10 ppm as TWA; A3 (confirmed animal carcinogen with unknown relevance to humans). MAK: 12 mg/m³, 2 ppm; peak limitation category: II(2); skin absorption (H); carcinogen category: 4; pregnancy risk group: C. EU-OEL: 12 mg/m³, 2 ppm as TWA; 60 mg/m³, 10 ppm as STEL; (skin)

ENVIRONMENT
The substance is very toxic to aquatic organisms. Bioaccumulation of this chemical may occur in fish.

NOTES
Depending on the degree of exposure, periodic medical examination is suggested. Do NOT take working clothes home.

ADDITIONAL INFORMATION

EC Classification
Symbol: Xn, N; R: 36-40-50/53; S: (2)-36/37-46-60-61

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